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Why blending bananas with berries can blunt the very thing you wanted from the berries
The morning smoothie has a kind of cultural sacredness. Berries, banana, maybe some yogurt or milk, maybe a scoop of greens powder, blend, drink, feel virtuous. A 2023 study that resurfaced in a Health.com piece this month suggests the banana piece of that ritual may be canceling out one of the better reasons to include the berries in the first place. What the research found The study was led by Dr. Javier Ottaviani and colleagues, published in Food & Function in 2023. The te
Joyce Knieff, ND, LAc
42 minutes ago5 min read


Is alcohol part of a healthy lifestyle? What the current evidence actually says
For years, the story told around dinner tables was that a glass of red wine with the meal was good for the heart. Medscape just ran a piece walking through how much that story has shifted, and the shift is one of the cleaner examples of what happens when better methods are applied to an old question. The headline is not new. The supporting evidence underneath the headline is. What the research found The longstanding "J-shaped curve" idea, the one suggesting moderate drinkers
Joyce Knieff, ND, LAc
1 day ago5 min read


Inulin, omega-3, and synbiotics: what a new inflammation study actually compared
Inflammation is one of those words that has been stretched almost to meaninglessness in wellness marketing. Almost every supplement, every diet, and every protocol claims to fight it. So when a paper drops that actually measures dozens of specific inflammatory markers across three different dietary interventions, it is worth slowing down to look at what was tested, what changed, and what the design can support. What the research found The study was published in October 2025 i
Joyce Knieff, ND, LAc
2 days ago5 min read


Fruit, juice, smoothies, and a small study on mood: reading the headlines carefully
A headline traveled through the wellness internet last month claiming that a "simple dietary change" was linked to lower depression scores. The change in question was including fruit juice and smoothies in the recommended 5-a-day of fruits and vegetables. The story is more nuanced than the headline suggests, and the funding source of the underlying study makes the careful read essential. What the research found The trial, published in the British Journal of Nutrition, was a f
Joyce Knieff, ND, LAc
3 days ago6 min read


Glucosamine, joints, and a worrying new signal in Alzheimer's research
Glucosamine has been one of the most popular over-the-counter joint supplements for decades. It is on the shelf at every pharmacy, in every wellness club's monthly subscription box, and tucked into countless multivitamin stacks for people in their fifties and sixties. The general impression has been that it is safe, mildly helpful for knee aches, and basically harmless. A new study in Nature Metabolism complicates that picture in a way that deserves attention, not panic. What
Joyce Knieff, ND, LAc
6 days ago5 min read


What a new randomized trial says about vitamin D in pregnancy and children's cognition at age 10
Prenatal vitamins are one of the few areas of medicine where almost everyone agrees something is worth taking, and almost no one agrees on how much. A new analysis just out in JAMA Network Open weighs in on one specific question: when pregnant women take a higher dose of vitamin D than the standard prenatal recommendation, can you measure a difference in their children a decade later? The answer the researchers reached is qualified, and the qualifications matter. What the res
Joyce Knieff, ND, LAc
Jun 294 min read


A new way to think about trauma: what predictive processing adds to the conversation
A piece in PsyPost recently pitched a new wave of trauma research as a challenge to Bessel van der Kolk's The Body Keeps the Score. The science underneath is more modest than that headline suggests. What is actually happening is more interesting and more useful. A growing group of researchers is testing a model of how trauma shapes the brain that focuses less on memory storage and more on prediction. This blog walks through that work carefully and with the understanding that
Joyce Knieff, ND, LAc
Jun 267 min read


A small new trial on peppermint oil and blood pressure — what it does and does not tell us
Patients ask me almost weekly whether there is a natural way to bring blood pressure down without going straight to medication. A new randomized controlled trial in PLoS One looked at exactly that question with peppermint oil, and the numbers got attention online before most clinicians had a chance to read the paper. So let me walk through what the study actually showed, what it does not show, and where it fits in the bigger conversation about prehypertension. TL;DR: A small
Joyce Knieff, ND, LAc
Jun 256 min read


What a new aging study on phosphatidylcholine tells us about mitochondria, choline, and getting older
Mitochondria get a lot of airtime in longevity conversations, and most of it skips past the part that actually matters in clinic. The cells are not running out of mitochondria as we age. They are running out of well-maintained mitochondrial membranes. A new paper in Nature Communications puts a finger on one specific membrane lipid, phosphatidylcholine, and shows that its decline with age is one of the things that pushes mitochondria into their tired late-life state. The inte
Joyce Knieff, ND, LAc
Jun 245 min read


When the diet itself is the experiment: what a small ketogenic trial tells us about Parkinson's
When someone is diagnosed with Parkinson's disease, the questions that follow almost never stop at "what medication should I take." People want to know what they can do at the kitchen table, in the grocery store, on a Tuesday afternoon. So when a small feasibility trial out of the National University of Natural Medicine in Portland tested whether people with Parkinson's could actually stick to a modified ketogenic diet for 12 weeks, that question moved one inch closer to an a
Joyce Knieff, ND, LAc
Jun 237 min read


One Patient, One Dose, One Headline: What a Psilocybin Case Report Can and Cannot Tell Us About Dementia
A case report out of Brazil has been making the rounds this month, with headlines like "Huge Psilocybin Dose Has Incredible Effect on Elderly Dementia Patient." The story is moving, the implications sound enormous, and the temptation to extrapolate is almost overwhelming. It is also the kind of story that begs to be read carefully, because the gap between what the case actually describes and what a worried family member might do with it is wide enough to cause harm. TL;DR: A
Joyce Knieff, ND, LAc
Jun 196 min read


When a Promising Herbal Headline Meets a Hard Look at the Evidence: Bupleurum for Epilepsy
Epilepsy is one of those diagnoses that often leaves patients searching for any additional option. The standard antiepileptic medications work well for many people, but a meaningful share of patients continue to have breakthrough seizures, or live with side effects from the drugs that make their quality of life harder than they want it to be. Into that search comes a recent paper out of China examining a class of traditional Chinese medicine formulas built around the herb Bup
Joyce Knieff, ND, LAc
Jun 186 min read


Three New Studies on Food Additives: What the Headlines Got Right, and What They Left Out
Health headlines this month have been heavy on food additives, with colorings linked to type 2 diabetes and cancer, and preservatives linked to hypertension and cardiovascular disease. The headlines are not wrong, and they are based on three solid studies from a respected French research cohort. The story underneath the headlines, though, is more interesting and more useful than "this additive causes that disease." TL;DR: Three large French studies link food colorings and pre
Joyce Knieff, ND, LAc
Jun 176 min read


How Fiber Trains the Gut to Handle Sugar (and Protect the Liver)
Most of the conversation about fructose in the last decade has been a one-note song. Too much fructose is hard on the liver. Too much fructose drives fatty liver disease. Cut back on added sugar, watch your sweetened drinks, read your labels. The advice is sensible and the science behind it is sound. What has been missing from the conversation is the role of the gut microbes that sit between your plate and your liver, and a new paper out of UC Irvine has just delivered a stri
Joyce Knieff, ND, LAc
Jun 166 min read


A Diabetes Drug Class Showing Up in Mast Cell Conversations: What the GLP-1 Case Series Actually Says
If you live with Mast Cell Activation Syndrome (MCAS), you have probably watched the cycle of "promising new treatment" headlines come and go. Antihistamines help, until they don't. Cromolyn helps some people and does nothing for others. Biologics work for a subset. The list of options grows, yet the unanswered question stays the same. Why does the body's immune-control system stay stuck in the "on" position? Now a familiar name from a different specialty is starting to show
Joyce Knieff, ND, LAc
Jun 155 min read


Reishi Mushroom: What the New Lab Research Adds, and What It Doesn't
Reishi mushroom (Ganoderma lucidum) has been on shelves and in tea blends for so long that it might feel like the science around it is settled. It is anything but. A new paper out of Zhejiang Gongshang University in China takes a closer look at what actually happens to the active compounds in reishi when they hit the digestive tract, how those compounds interact with the gut microbiome, and what immune cells do in response. The findings are mechanistically interesting, with o
Joyce Knieff, ND, LAc
Jun 127 min read


Grapes, Sun Damage, and a Headline That Needs Some Context
Memorial Day weekend has come and gone, the sunscreen aisle has been picked over, and a news cycle just rolled through with a headline that probably reached your social feed at least once: scientists discover grapes can "reprogram" your skin against sun damage. The science underneath the headline is genuinely interesting. It is also more modest than the headline suggests, and there are a few important pieces of context that make the picture more useful for actual decision-mak
Joyce Knieff, ND, LAc
Jun 117 min read


The Newest GLP-1-Class Trial Results, and What They Don't Solve
The conversation about weight-loss medications has changed faster than almost any other area of medicine over the past five years. Patients are asking about it. Friends are using it. Headlines about another phase 3 trial seem to land every few weeks. This week the news came from a class of drug that goes one step beyond the GLP-1 medications already on the market. A phase 3 trial called TRIUMPH-1, run by the manufacturer, reported weight-loss results that look more like what
Joyce Knieff, ND, LAc
Jun 108 min read


When Zero-Sugar Isn't Quite What It Seems: A Closer Look at Sugar Substitutes
Walk down any grocery aisle and the words on the labels almost write themselves. Zero sugar. No calories. Keto-friendly. Diet. For decades, the assumption built into all of that marketing has been that swapping out sugar for a sweetener was a free trade, with the calories gone and nothing meaningful taken on in their place. The newer research is starting to complicate that picture. A Medscape review in late May pulled together a body of evidence that has been building for the
Joyce Knieff, ND, LAc
Jun 97 min read


A Surprising Result From the Peppermint Aisle: Blood Pressure and a Common Kitchen Herb
If you've ever been told you have prehypertension or stage 1 hypertension, you probably know the feeling that follows. The numbers aren't quite bad enough to start medication. They aren't quite good enough to ignore. You leave the appointment with a vague directive to lose some weight, walk more, eat less salt, and recheck in three months. For a lot of people, that middle zone is where blood pressure drifts in the wrong direction. A small trial out of the United Kingdom, just
Joyce Knieff, ND, LAc
Jun 87 min read
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